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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 15.15
Human Site: Y101 Identified Species: 25.64
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 Y101 H N Q T G K K Y Q W D A E T Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 Y101 H N Q T G K K Y Q W D A E T Q
Dog Lupus familis XP_532204 495 54438 Y101 H N Q T G K R Y Q W D A E T Q
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 Y101 H N H T G K K Y K W D A E T Q
Rat Rattus norvegicus Q7TSF2 588 64736 F122 P E I Q T A Q F N W D P E T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 G95 V S S C P H P G K L V G V F R
Chicken Gallus gallus NP_001026257 484 53539 W99 W D A D T Q G W I L G S F F Y
Frog Xenopus laevis Q6INC8 576 63887 F109 L V I E Q A Q F N W D P E T V
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 F122 A V M Q P A Q F N W D P E T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 F101 D D S Q D G E F A W S S A L Q
Honey Bee Apis mellifera XP_395682 508 56831 F100 N E Y F E K E F D W D S K T Q
Nematode Worm Caenorhab. elegans Q03567 493 52719 I99 Y G Y I G S Q I I G G H L A S
Sea Urchin Strong. purpuratus XP_780445 542 58846 F104 Q S N T T Q K F N W D S N T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 Y163 I L P M S Q E Y N W S S A T V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 26.6 N.A. 0 0 26.6 26.6 N.A. 13.3 33.3 6.6 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 40 N.A. 20 26.6 40 40 N.A. 40 66.6 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 22 0 0 8 0 0 29 15 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 0 8 8 0 0 0 8 0 65 0 0 0 0 % D
% Glu: 0 15 0 8 8 0 22 0 0 0 0 0 50 0 0 % E
% Phe: 0 0 0 8 0 0 0 43 0 0 0 0 8 15 0 % F
% Gly: 0 8 0 0 36 8 8 8 0 8 15 8 0 0 0 % G
% His: 29 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 15 8 0 0 0 8 15 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 36 29 0 15 0 0 0 8 0 8 % K
% Leu: 8 8 0 0 0 0 0 0 0 15 0 0 8 8 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 29 8 0 0 0 0 0 36 0 0 0 8 0 0 % N
% Pro: 8 0 8 0 15 0 8 0 0 0 0 22 0 0 0 % P
% Gln: 8 0 22 22 8 22 29 0 22 0 0 0 0 0 43 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 0 15 15 0 8 8 0 0 0 0 15 36 0 0 8 % S
% Thr: 0 0 0 36 22 0 0 0 0 0 0 0 0 72 0 % T
% Val: 8 15 0 0 0 0 0 0 0 0 8 0 8 0 29 % V
% Trp: 8 0 0 0 0 0 0 8 0 79 0 0 0 0 0 % W
% Tyr: 8 0 15 0 0 0 0 36 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _